Electron Transport & Oxidative Phosphorylation

Electron Transport & Oxidative Phosphorylation is a metabolic pathway that uses the energy released from the Citric Acid Cycle and oxygen to produce ATP. It is the major ATP production mechanism in human carbohydrate metabolism. NADH-coenzyme Q oxidoreductase (complex I) NADH-quinone oxidoreductase NADH:ubiquinone oxidoreductase NADH quinone oxidoreductase (NQO1) with inhibitor dicoumarol The reaction that is catalyzed by this enzyme is the two electron oxidation of by or ubiquinone (represented as Q in the equation below), a lipid-soluble quinone that is found in the mitochondrion membrane: NADH + Q + 5H+(matrix) ⟶ NAD+ + QH2 +4H+(intermembrane) The start of the reaction, and indeed of the entire electron chain, is the binding of a NADH molecule to complex I and the donation of two electrons. The electrons enter complex I via a prosthetic group attached to the complex, (FMN). The addition of electrons to FMN converts it to its reduced form, FMNH2. The electrons are then transferred through a series of iron–sulfur clusters: the second kind of prosthetic group present in the complex. There are both [2Fe–2S] and [4Fe–4S] iron–sulfur clusters in complex I. Succinate-Q oxidoreductase (complex II) Succinate Dehydrogenase Complex III Complex III of Electron Transport Chain To view automatically seeded indices concerning Electron Transport & Oxidative Phosphorylation See: Electron Transport

spinqualitylabelsall models NADPH dehydrogenase complex with FAD and dicoumarol 2f1o Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image