4mlk

3.05A resolution structure of CT584 from Chlamydia trachomatis3.05A resolution structure of CT584 from Chlamydia trachomatis

Structural highlights 4mlk is a 1 chain structure with sequence from Chlamydia trachomatis 434/Bu. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function A0A0H3MCR9_CHLT2 Publication Abstract from PubMed Chlamydia trachomatis is a major cause of various diseases, including blinding trachoma and pelvic inflammatory disease, and is the leading reported sexually transmitted bacterial infection worldwide. All pathogenic Chlamydiae spp. utilize a supramolecular syringe, or type III secretion system (T3SS), to inject proteins into their obligate host in order to propagate infection. Here, the structure of CT584, a T3SS-associated protein, that has been refined to a resolution of 3.05 A is reported. The CT584 structure is a hexamer comprised of a trimer of dimers. The structure shares a high degree of similarity to the recently reported structure of an orthologous protein, Cpn0803, from Chlamydia pneumoniae, which highlights the highly conserved nature of this protein across these chlamydial species, despite different tissue tropism and disease pathology. Structure of CT584 from Chlamydia trachomatis refined to 3.05 A resolution.,Barta ML, Hickey J, Kemege KE, Lovell S, Battaile KP, Hefty PS Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Nov;69(Pt 11):1196-201., doi: 10.1107/S1744309113027371. Epub 2013 Oct 26. PMID:24192348 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

spinqualitylabelsall models 4mlk, resolution 3.05Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image