1dpn

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B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINEB-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE

Structural highlights

1dpn is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Publication Abstract from PubMed

We have determined single crystal structures of an A-DNA decamer and a B-DNA dodecamer at 0.83 and 0.95 A, respectively. The resolution of the former is the highest reported thus far for any right-handed nucleic acid duplex and the quality of the diffraction data allowed determination of the structure with direct methods. The structures reveal unprecedented details of DNA fine structure and hydration; in particular, we have reexamined the overall hydration of A- and B-form DNA, the distribution of water around phosphate groups, and features of the water structure that may underlie the B to A transition.

X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.,Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M Biopolymers. 1998;48(4):234-52. PMID:10699842[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

  1. Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M. X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution. Biopolymers. 1998;48(4):234-52. PMID:10699842 doi:<234::AID-BIP4>3.0.CO;2-H http://dx.doi.org/10.1002/(SICI)1097-0282(1998)48:4<234::AID-BIP4>3.0.CO;2-H

1dpn, resolution 0.95Å

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