Structure of Thyrotropin-Releasing Hormone Receptor bound with Taltirelin.Structure of Thyrotropin-Releasing Hormone Receptor bound with Taltirelin.

Structural highlights

7x1t is a 6 chain structure with sequence from Bos taurus, Homo sapiens, Rattus norvegicus and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[GBG2_BOVIN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

7x1t, resolution 3.26Å

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OCA