Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 1)Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 1)

Structural highlights

4cgx is a 2 chain structure with sequence from Thogoto thogotovirus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[PA_THOGV] Initiates transcription by a unique cap-stealing mechanism that involves the cleavage of only the m(7)GpppAm structure from cellular hnRNAs.

See Also

4cgx, resolution 2.70Å

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OCA