4c84

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zebrafish ZNRF3 ectodomain crystal form Izebrafish ZNRF3 ectodomain crystal form I

Structural highlights

4c84 is a 2 chain structure with sequence from Danio rerio. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[ZNRF3_DANRE] E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components.

See Also

4c84, resolution 1.60Å

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OCA