1gen
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C-TERMINAL DOMAIN OF GELATINASE A
OverviewOverview
The crystal structure of the haemopexin-like C-terminal domain of, gelatinase A reveals that it is a four-bladed beta-propeller protein. The, four blades are arranged around a channel-like opening in which Ca2+ and a, Na-Cl+ ion pair are bound.
DiseaseDisease
Known diseases associated with this structure: Osteolysis, idiopathic, Saudi type OMIM:[120360], Winchester syndrome OMIM:[120360]
About this StructureAbout this Structure
1GEN is a Single protein structure of sequence from Homo sapiens with ZN, CA, CL and NA as ligands. Active as Gelatinase A, with EC number 3.4.24.24 Full crystallographic information is available from OCA.
ReferenceReference
Crystal structure of the haemopexin-like C-terminal domain of gelatinase A., Libson AM, Gittis AG, Collier IE, Marmer BL, Goldberg GI, Lattman EE, Nat Struct Biol. 1995 Nov;2(11):938-42. PMID:7583664
Page seeded by OCA on Mon Nov 12 17:03:45 2007