Co-crystal structure of Deinococcus radiodurans uracil-DNA glycosylase and the C-terminus of the single-stranded DNA-binding proteinCo-crystal structure of Deinococcus radiodurans uracil-DNA glycosylase and the C-terminus of the single-stranded DNA-binding protein

Structural highlights

3ufm is a 2 chain structure with sequence from Deira. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:DR0689, DR_0689, ung (DEIRA)
Activity:Uracil-DNA glycosylase, with EC number 3.2.2.27
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[UNG_DEIRA] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity). [SSB_DEIRA] This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair (By similarity).

See Also

3ufm, resolution 1.95Å

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OCA