DNA mismatch repair protein 3D structures

DNA mismatch repair protein

Updated on 03-July-2022

{"openlevels":0}

*MutL

• • 4e4w, 4fmo – yMutL C-terminal – yeast
    
  • 4fmn – yMutL C-terminal + DNA repair peptide
    
  • 3gab, 3kdg, 3kdk – MutL C-terminal – Bacillus subtilis
    
  • 3ncv – NgMutL – Neisseria gonorrhoeae
    
  • 5z41, 5z42 – AaMutL – Aquifex aeolicus
    
  • 5b42 – AaMutL C-terminal 325-425
    
  • 5x9y – AaMutL ATPase domain 9-315
    
  • 6lzk – AaMutL ATPase domain (mutant)
    
  • 6lzj – AaMutL ATPase domain + AMPPCP
    
  • 6lzi – AaMutL ATPase domain + ADP
    
  • 1bkn – EcMutL N-terminal – Escherichia coli
    
  • 1x9z – EcMutL C-terminal
    
  • 1b63 – EcMutL + ANP
    
  • 1nhh, 1nhi, 1nhj – EcMutL (mutant) + ANP
    
  • 1b62 – EcMutL + ADP
    
  • 7p8v – EcMutL + DNA + ANP – Cryo EM
    

*MutS

• • 3k0s, 3zlj – EcMutS (mutant) + DNA
    
  • 1e3m, 1oh5, 1oh6, 1oh7, 1oh8 – EcMutS + DNA + ADP
    
  • 1ng9, 1wb9, 1wbb, 1wbd, 2wtu – EcMutS (mutant) + DNA + ADP
    
  • 1w7a – EcMutS + DNA + ATP
    
  • 7ai5, 7ai6, 7ai7 – EcMutS + DNA + ATP – Cryo EM
    
  • 7ou0, 7ou2 – EcMutS + ADP – Cryo EM
    
  • 6i5f – EcMutS (mutant) + ADP
    
  • 7oto – EcMutS + AMPPNP – Cryo EM
    
  • 7ou4 – EcMutS + ATP + ADP – Cryo EM
    
  • 5x9w, 5yk4 – NgMutS + ADP
    
  • 1ewr – TaMutS – Thermus aquaticus
    
  • 1ewq – TaMutS + DNA
    
  • 1fw6, 1nne – TaMutS + DNA + ADP
    

*MutS+MutL

• • 7aib, 7aic – EcMutS (mutant) + MutL (mutant) + ANP + DNA – Cryo EM
    
  • 5akb, 5akc, 5akd – EcMutS (mutant) + MutL N-terminal 1-349 (mutant) + ANP
    

*MutH

• • 1azo, 2azo – EcMutH
    
  • 2aoq, 2aor – MutH + DNA - Haemophilus influenzae
    

*MLH1

• • 3rbn – hMLH1 – human
    
  • 4p7a – hMLH1 + ADP
    

*MLH1+MLH3

• • 6rmn, 6shx, 6sns, 6snv – yMLH1 + MLH3
    

*MLH2+MLH3

• • 3thw, 3thx, 3thy, 3thz – hMLH1 + MLH3 + DNA + ADP
    

*MSM3

• • 3vld, 3vle, 4a3t, 4fp7 – yHSM3
    
  • 3vlf, 4a3v, 4jpo – yHSM3 + Rpt1
    

*MSH6

• • 2gfu – hMSH6 – NMR
    
  • 6oqm – hMSH6 PWWP domain 87-198
    

*MSH6+MSH2

• • 2o8b, 2o8c, 2o8d, 2o8e, 2o8f – hMSH6 + MSH2 + DNA + ADP
    

*PMS1

• • 2cs1 – hPMS1 HMG domain – NMR
    
  • 3h4l – yPMS1 N-terminal + ANP
    

*PMS2

• • 1h7s, 6mfq – hPMS2 N-terminal 1-365
    
  • 7rcb – hPMS2 N-terminal (mutant)
    
  • 1h7u – hPMS2 N-terminal + ATPgS
    
  • 1ea6 – hPMS2 N-terminal + ADP
    
  • 7rci, 7rck – hPMS2 N-terminal + ATP