Art:Dodecapod

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Tailed bacteriophages and herpesviruses have a DNA "pipe" in their capsids, called a portal protein[1]. The images here depict 7sya, a homo-dodecamer[1]. In the animation at right, each of the 12 protein chains is colored amino to carboxy spectrum (N->C Rainbow):

N               C

All images and the animation were generated with FirstGlance in Jmol (version 4.0, not yet released in mid-May 2022). The two sides of the oblate structure (or tube with a flange) are designated the N-face (face with amino termini) and the C-face (face with carboxy termini).

References & NotesReferences & Notes

  1. 1.0 1.1 David Hou CF, Swanson NA, Li F, Yang R, Lokareddy RK, Cingolani G. Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3. J Mol Biol. 2022 Mar 9;434(9):167537. doi: 10.1016/j.jmb.2022.167537. PMID:35278476 doi:http://dx.doi.org/10.1016/j.jmb.2022.167537