Crystal structure of H.pylori phosphopantetheine adenylyltransferase mutant I4V/N76YCrystal structure of H.pylori phosphopantetheine adenylyltransferase mutant I4V/N76Y

Structural highlights

3nv7 is a 1 chain structure with sequence from Campylobacter pylori. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:coaD, kdtB, HP_1475 (Campylobacter pylori)
Activity:Pantetheine-phosphate adenylyltransferase, with EC number 2.7.7.3
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[COAD_HELPY] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.[HAMAP-Rule:MF_00151]

3nv7, resolution 1.75Å

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OCA