2epr

Solution structure of the secound zinc finger domain of Zinc finger protein 278Solution structure of the secound zinc finger domain of Zinc finger protein 278

2epr is a 1 chain structure with sequence from Human. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:	PATZ1, PATZ, RIAZ, ZBTB19, ZNF278, ZSG (HUMAN)
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

[PATZ1_HUMAN] Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1.

[PATZ1_HUMAN] Transcriptional repressor.^[1]

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

↑ Fedele M, Benvenuto G, Pero R, Majello B, Battista S, Lembo F, Vollono E, Day PM, Santoro M, Lania L, Bruni CB, Fusco A, Chiariotti L. A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor. J Biol Chem. 2000 Mar 17;275(11):7894-901. PMID:10713105