3bfx

Crystal structure of human sulfotransferase SULT1C1 in complex with PAPCrystal structure of human sulfotransferase SULT1C1 in complex with PAP

Structural highlights 3bfx is a 2 chain structure with sequence from Human. This structure supersedes the now removed PDB entries 2etg and 1zhe. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: Gene: SULT1C2, SULT1C1 (HUMAN) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [ST1C2_HUMAN] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Sulfotransferase

spinqualitylabelsall models 3bfx, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image