1ui9

Crystal analysis of chorismate mutase from thermus thermophilusCrystal analysis of chorismate mutase from thermus thermophilus

1ui9 is a 1 chain structure with sequence from "flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971. The April 2010 RCSB PDB Molecule of the Month feature on Concanavalin A and Circular Permutation by David Goodsell is 10.2210/rcsb_pdb/mom_2010_4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	,
Related:	1ode, 1ufy
Activity:	Chorismate mutase, with EC number 5.4.99.5
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

[AROH_THETH] Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.^[1]

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

↑ Helmstaedt K, Heinrich G, Merkl R, Braus GH. Chorismate mutase of Thermus thermophilus is a monofunctional AroH class enzyme inhibited by tyrosine. Arch Microbiol. 2004 Mar;181(3):195-203. Epub 2004 Jan 15. PMID:14727008 doi:http://dx.doi.org/10.1007/s00203-003-0639-z