Sandbox GGC6
Neurotrophin-4Neurotrophin-4
Neurotrophin-4 (NFT-4) is a neuronal growth factor that influences nerve cell proliferation through selective and non-covalent interactions with the nerve growth factor receptor.
FunctionNFT-4 functions as a growth factor in many biological pathways and processes to induce neuronal proliferation. Biological ProcessesPositive regulation of neurotrophin TRK receptor signaling pathway: NFT-4 functions as a ligand when binding to neurotrophin receptor tyrosine kinase NTRK2. Auto-phosphorylated NTRK2 dimers that are formed on tyrosine residues in receptor tail as a result of NFT-4 binding. Neuron projection morphogenesis: Generating projection structures of a neuron,. Ganglion mother cell fate determination, epidermis development, innervation Nerve invading tissue and coming out DiseaseRelevanceStructural highlightsThis is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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ReferencesReferences
- ↑ Mitre M, Mariga A, Chao MV. Neurotrophin signalling: novel insights into mechanisms and pathophysiology. Clin Sci (Lond). 2017 Jan 1;131(1):13-23. doi: 10.1042/CS20160044. PMID:27908981 doi:http://dx.doi.org/10.1042/CS20160044