Proteopedia:Featured SEL/8

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Revision as of 07:38, 10 March 2021 by Jaime Prilusky (talk | contribs) (New page: <table> <tr><td> <imagemap> Image:Alphafold2-orf8-vs-7jx6-300x300.gif|center default Theoretical_models#2020:_CASP_14 </imagemap> </td></tr> <tr><td><div class='scrolling '>'''BREAKTHR...)
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BREAKTHROUGH in protein structure prediction!

by Eric Martz
After decades of slow progress by many groups, in 2020, AlphaFold2 proved able to accurately predict the detailed structures of two-thirds of single protein domains from their amino acid sequences. Pictured is AlphaFold2's prediction for the ORF8 protein of SARS-CoV-2 (black), compared with a subsequently published X-ray crystallographic structure (colors). ORF8 contributes to virulence in COVID-19. >>> Visit this page >>>

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Jaime Prilusky, Eric Martz