2dxe

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Crystal structure of nucleoside diphosphate kinase in complex with GDPCrystal structure of nucleoside diphosphate kinase in complex with GDP

Structural highlights

2dxe is a 2 chain structure with sequence from Pyrococcus horikoshii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:ndk (Pyrococcus horikoshii)
Activity:Nucleoside-diphosphate kinase, with EC number 2.7.4.6
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[NDK_PYRHO] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2dxe, resolution 1.70Å

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