Nuclear receptors

Under development!!! Nuclear receptor structure is composed of 5 domains - A/B: N-terminal regulatory domain contains activation function 1 (residues 101-370), activation function 5 (residues 360-485) and dimerization surface (residues 1-36 and 370-494). C: DNA binding domain (DBD) D: Hinge region between DBD and LBD E: Ligand binding domain (LBD) containing an which binds intramolecularly the N-terminal FXXFL motif or coactivators with the same motif (Human androgen receptor ligand-binding domain complex with modulator; PDB code 3b5r). Water molecules are shown as red spheres. F: C-terminal domain Thyroid Hormone Receptor-like Peroxisome Proliferator-Activated Receptors PPARγ PPAR-gamma Pioglitazone is a selective agonist for Peroxisome Proliferator-Activated Receptor Gamma Estrogen Receptor-like Estrogen receptor Ivan Koutsopatriy estrogen receptor Estrogen receptor alpha Estrogen receptor#Structure of estradiol metal chelate and estrogen receptor complex: The basis for designing a new class of SERMs Estrogen receptor#Estrogen receptor α complexed with raloxifene and a corepressor peptide Tamoxifen and the Estrogen receptor Estrogen receptor beta Student Project 10 for UMass Chemistry 423 Spring 2015

spinqualitylabelsall models Human androgen receptor ligand-binding domain complex with modulator (PDB code 3b5r) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image