Urokinase 3D Structures

3D Structures of urokinase3D Structures of urokinase

Updated on 09-January-2021 - For a general description of the protein see Urokinase

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• Urokinase' Domains - N terminal 21-163; Kringle 69-153; catalytic 179-431
  • 2i9a - hUK Hc N terminal - human
    
  • 1urk - hUK Hc N terminal – NMR
    
  • 1kdu – hUK kringle domain - NMR
    
  • 4dva – hUK catalytic domain
    
  • 4xsk - hUK catalytic domain (mutant)
    
  • 5lhs - UK catalytic domain (mutant) - mouse
    
• Urokinase catalytic domain complex with inhibitors
  • 1c5w, 1c5x, 1c5y, 1c5z, 1lmw, 3ig6, 4fu7, 4fu8, 4fu9, 4fub, 5xg4, 5wxs - hUK + inhibitor
    
  • 1f92, 1gi7, 1gi8, 1gi9, 1gj7, 1gj8, 1gj9, 1gja, 1gjb, 1gjc, 1gjd, 1o3p, 1o5a, 1o5b, 1o5c, 1sc8, 1vj9, 1vja, 2o8t, 2o8u, 2o8w, 3kgp, 3khv, 3kid, 3mhw, 3mwi, 3ox7, 3oy5, 3oy6, 4h42, 4mnv,5wxt - hUK (mutant) + inhibitor
    
  • 1fv9 – hUK (mutant) + benzimidazole derivative
    
  • 5yc6, 5yc7 - hUK (mutant) + benzylamine derivative
    
  • 1f5k - hUK (mutant) + benzamidine derivative
    
  • 1f5l - hUK (mutant) + amiloride derivative
    
  • 1owd, 1owe, 1owh, 1owi, 1owj, 1owk, 1sqa, 1sqo, 1u6q, 1sqt, 4fuc, 4fud, 4fue, 4fuf, 4fug, 4fuh, 4fui, 4fuj- hUK + naphthamidine inhibitor
    
  • 6nmb- hUK + tranexamic acid inhibitor
    
  • 1ejn - hUK (mutant) + urea derivative inhibitor
    
  • 2vin, 2vio, 2vip, 2viq, 2viv, 2viw - hUK (mutant) + mexiletine derivative
    
  • 3qn7, 4jk5, 4jk6, 4x1n, 4x1q, 4x1r, 4x1s, 4x0w, 4x1p, 4zhl, 4zhm, 4zkn, 4zko, 4zkr, 4zks - hUK (mutant) + peptide inhibitor
    
  • 2nwn, 3m61, 4gly, 4mnw, 4mnx, 4mny, 4os1, 4os2, 4os4, 4os5, 4os6, 4os7 - hUK (mutant) + bicyclic peptide
    
  • 2vnt, 2r2w - hUK + guanidine derivative
    
  • 5xg4 - hUK + quercetin
    
  • 1w0z, 1w10, 1w11, 1w12, 1w13, 1w14 - hUK + alanineamide derivative
    
  • 6xvd- hUK + UPAIN-1-W3F
    
  • 5wxf- hUK + UPAIN-2
    
  • 5wxo- hUK + UPAIN-2-W3F
    
  • 5wxp- hUK + UPAIN-2-3-W3F
    
  • 5wxr- hUK + UPAIN-2-4-W3F
    
• Urokinase complex with protein
  • 2fd6 – hUK Hc N terminal + antibody + UK receptor
    
  • 3bt1, 3bt2 - hUK Hc N terminal + vitronectin + UK receptor
    
  • 4k24 - hUK Hc N terminal + vitronectin + antibody
    
  • 3laq, 3u73 - hUK Hc N terminal + UK receptor
    
  • 2i9b - hUK Hc N terminal + UK receptor (mutant)
    
  • 3pb1 - hUK Hc catalytic domain (mutant) + UK inhibitor
    
  • 4dw2 - hUK B chain catalytic domain + antibody
    
  • 5hgg - hUK catalytic domain (mutant) + antibody
    
  • 5lhn, 5lhr - mUK catalytic domain (mutant) + antibody
    
  • 5lhp, 5lhq - mUK catalytic domain (mutant) + antibody + inhibitor