5zj2

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Crystal structure of NDM-1 in complex with D-captoprilCrystal structure of NDM-1 in complex with D-captopril

Structural highlights

5zj2 is a 1 chain structure with sequence from "bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:blaNDM-1 ("Bacillus pneumoniae" (Schroeter 1886) Flugge 1886)
Activity:Beta-lactamase, with EC number 3.5.2.6
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.

See Also

5zj2, resolution 1.10Å

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