Crystal structure of the bacterial cellulose secretion regulator BcsE, residues 217-523, with bound c-di-GMP.Crystal structure of the bacterial cellulose secretion regulator BcsE, residues 217-523, with bound c-di-GMP.

Structural highlights

6tj0 is a 2 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
NonStd Res:
Gene:bcsE, yhjS, b3536, JW3504 (ECOLI)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[BCSE_ECOLI] Binds bis-(3'-5') cyclic diguanylic acid (c-di-GMP), the ability to bind c-di-GMP is important for its function (PubMed:24942809).[1]

References

  1. Fang X, Ahmad I, Blanka A, Schottkowski M, Cimdins A, Galperin MY, Romling U, Gomelsky M. GIL, a new c-di-GMP-binding protein domain involved in regulation of cellulose synthesis in enterobacteria. Mol Microbiol. 2014 Aug;93(3):439-52. doi: 10.1111/mmi.12672. Epub 2014 Jul 1. PMID:24942809 doi:http://dx.doi.org/10.1111/mmi.12672

6tj0, resolution 2.20Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA