2wr6

Structure of the complex of RBP4 with linoleic acidStructure of the complex of RBP4 with linoleic acid

Structural highlights 2wr6 is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: , Related: 1rbp, 1jyd, 1jyj, 2wq9, 1qab, 2wqa Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease [RET4_HUMAN] Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium. Function [RET4_HUMAN] Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Retinol-binding protein 3D structures

spinqualitylabelsall models 2wr6, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image