NudT16

IntroductionIntroduction

NudT16 is a hydrolase and belongs to the nucleoside diphosphate-linked moiety X (Nudix) family. This protein regulates levels of 53BP1 which is a protein that recruits other proteins to the site of a DNA breakage. NudT16 has also shown in vitro to remove ADP-ribosylation through its hydrolase activities.

StructureStructure

NudT16 is a dimer

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Crystal structure of HsNUDT16 in complex with diADPR (PDB entry 6B09)

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Tihitina Y Aytenfisu, Hannah Campbell, Sandra B. Gabelli, Michal Harel

NudT16

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IntroductionIntroduction

StructureStructure

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FunctionFunction

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NudT16

IntroductionIntroduction

StructureStructure

Your Heading Here (maybe something like 'Structure')Your Heading Here (maybe something like 'Structure')

FunctionFunction

DiseaseDisease

RelevanceRelevance

Structural highlightsStructural highlights

ReferencesReferences

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