NudT16 is a hydrolase and belongs to the nucleoside diphosphate-linked moiety X (Nudix) family. This protein regulates levels of 53BP1 which is a protein that recruits other proteins to the site of a DNA breakage. NudT16 has also shown in vitro to remove ADP-ribosylation through its hydrolase activities.
StructureStructure
NudT16
NudT16 is a dimer
Crystal structure of HsNUDT16 in complex with diADPR (soaked)