5jo7

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Henbane premnaspirodiene synthase (HPS), also known as Henbane vetispiradiene synthase (HVS) from Hyoscyamus muticusHenbane premnaspirodiene synthase (HPS), also known as Henbane vetispiradiene synthase (HVS) from Hyoscyamus muticus

Structural highlights

5jo7 is a 4 chain structure with sequence from Egyptian henbane. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Activity:Vetispiradiene synthase, with EC number 4.2.3.21
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[VTSS1_HYOMU] Sesquiterpene synthase that catalyzes the formation of vetispiradiene from trans,trans-farnesyl diphosphate. The initial internal cyclization produces the monocyclic intermediate germacrene A.

5jo7, resolution 2.15Å

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OCA