5jo3

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PDE5A for NaV1.7PDE5A for NaV1.7

Structural highlights

5jo3 is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:3',5'-cyclic-GMP phosphodiesterase, with EC number 3.1.4.35
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[PDE5A_HUMAN] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP.

See Also

5jo3, resolution 1.49Å

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