Nucleoside triphosphatase

Function Nucleoside triphosphatase or nucleoside triphosphate diphosphohydrolase (NTPase) is responsible for degradation of nucleotides to their monophosphate form. NTPase is found in mammals and in pathogenic microbes. In mammals NTPase hs a crucial role in regulation of purinergic signalling by hydrolysis of extracellular nucleotides. The function of NTPase in pathogens is still unknown.

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3D structures of nucleoside triphosphatase3D structures of nucleoside triphosphatase

Updated on 12-May-2020

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• Nucleoside triphosphatase 1
  • 4a57 - TgNTPase 1 - Toxoplasma gondii
    
  • 4a59 - TgNTPase 1 + AMP
    
• Nucleoside triphosphatase 2
  • 4jep - TgNTPase 2
    
  • 4a5b - TgNTPase 2 (mutant)
    
  • 4kh4, 4a5a - TgNTPase 2 (mutant) + AMPPNP
    
  • 4kh5, 4kh6 - TgNTPase 2 (mutant) + AMPNP
    
• Nucleoside triphosphatase Nudi
  • 6dt3 - Nudi - Klebsiella pneumoniae
    
  • 3oga, 3n77 - Nudi - Salmonella enterica
    
• Nucleoside triphosphatase cancer-related
  • 2i3b - NTPase - human- NMR
    
• Nucleoside triphosphatase
  • 3s86 - NTPase - Thermotoga maritima
    
  • 3agr - NTPase - Neospora caninum