The crystal structure of AAR-C294S in complex with ADO.The crystal structure of AAR-C294S in complex with ADO.

Structural highlights

6jzz is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Activity:[acyl-carrier-protein_reductase Long-chain acyl-[acyl-carrier-protein] reductase], with EC number 1.2.1.80
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[AAR_SYNE7] Catalyzes the NADP-dependent reduction of long-chain acyl-ACP to the corresponding fatty aldehyde. Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane, by producing the fatty aldehydes used by aldehyde decarbonylase.[1] [Q8KPT4_SYNE7] Catalyzes the decarbonylation of fatty aldehydes to alkanes.[HAMAP-Rule:MF_00931]

References

  1. Schirmer A, Rude MA, Li X, Popova E, del Cardayre SB. Microbial biosynthesis of alkanes. Science. 2010 Jul 30;329(5991):559-62. doi: 10.1126/science.1187936. PMID:20671186 doi:10.1126/science.1187936

6jzz, resolution 3.01Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA