Crystal structure of the murine cd44 hyaluronan binding domain complex with a small moleculeCrystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule

Structural highlights

5bzr is a 1 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:Cd44, Ly-24 (LK3 transgenic mice)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.

See Also

5bzr, resolution 1.15Å

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OCA