Template:STRUCTURE 1agq

File:1agq.gif

GLIAL CELL-DERIVED NEUROTROPHIC FACTOR FROM RAT


OverviewOverview

The crystal structure of glial cell-derived neurotrophic factor (GDNF) reveals two independent copies of the dimer that differ significantly through a hinge bending at the central, disulphide-rich region. GDNF is compared with other members of the TGF-beta family, and potential receptor binding surfaces are identified.

About this StructureAbout this Structure

1AGQ is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

ReferenceReference

X-ray structure of glial cell-derived neurotrophic factor at 1.9 A resolution and implications for receptor binding., Eigenbrot C, Gerber N, Nat Struct Biol. 1997 Jun;4(6):435-8. PMID:9187648 Page seeded by OCA on Fri May 2 10:14:54 2008

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