6j6t

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Crystal Structure of HDA15 HD domainCrystal Structure of HDA15 HD domain

Structural highlights

6j6t is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Activity:Histone deacetylase, with EC number 3.5.1.98
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[HDA15_ARATH] Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity).

6j6t, resolution 2.36Å

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OCA