Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with cytidineCrystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with cytidine

Structural highlights

6cvu is a 4 chain structure with sequence from Myctu. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:bioD, Rv1570, MTCY336.33c (MYCTU)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[BIOD_MYCTA] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.

See Also

6cvu, resolution 2.43Å

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OCA