5vsv

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Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P225Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P225

Structural highlights

5vsv is a 4 chain structure with sequence from "bacillus_perfringens"_veillon_and_zuber_1898 "bacillus perfringens" veillon and zuber 1898. This structure supersedes the now removed PDB entry 5uzo. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:guaB_2, guaB, ERS852446_02285, JFP838_13815 ("Bacillus perfringens" Veillon and Zuber 1898)
Activity:IMP dehydrogenase, with EC number 1.1.1.205
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[A0A127ELD1_CLOPF] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]

See Also

5vsv, resolution 2.21Å

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