6f7g

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Tryptophan Repressor TrpR from E.coli with 5-MethyltryptamineTryptophan Repressor TrpR from E.coli with 5-Methyltryptamine

Structural highlights

6f7g is a 2 chain structure with sequence from "bacillus_coli"_migula_1895 "bacillus coli" migula 1895. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:trpR, rtrY, b4393, JW4356 ("Bacillus coli" Migula 1895)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[TRPR_ECOLI] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

6f7g, resolution 1.66Å

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