4wr9

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Crystal Structure of Surfactant Protein-A DED Mutant (E171D/P175E/K203D)Crystal Structure of Surfactant Protein-A DED Mutant (E171D/P175E/K203D)

Structural highlights

4wr9 is a 1 chain structure with sequence from Buffalo rat. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:Sftpa1, Sftp-1, Sftp1, Sftpa (Buffalo rat)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[SFTPA_RAT] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.

4wr9, resolution 2.30Å

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OCA