1j2g

Crystal structure of Urate oxidase from Bacillus SP. TB-90 co-crystallized with 8-AzaxanthineCrystal structure of Urate oxidase from Bacillus SP. TB-90 co-crystallized with 8-Azaxanthine

Structural highlights

1j2g is a 4 chain structure with sequence from Bacsb. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	,
Related:	1uox
Activity:	Factor independent urate hydroxylase, with EC number 1.7.3.3
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[PUCL_BACSB] Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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OCA