6ub9

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Crystal structure of tryptophan synthase from M. tuberculosis - AMINOACRYLATE- AND BRD6309-BOUND FORMCrystal structure of tryptophan synthase from M. tuberculosis - AMINOACRYLATE- AND BRD6309-BOUND FORM

Structural highlights

6ub9 is a 8 chain structure with sequence from Myctu. This structure supersedes the now removed PDB entry 6dua. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , , , , ,
Gene:trpA, Rv1613, MTCY01B2.05 (MYCTU), trpB, Rv1612, MTCY01B2.04 (MYCTU)
Activity:Tryptophan synthase, with EC number 4.2.1.20
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[TRPA_MYCTU] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. [TRPB_MYCTU] The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine (By similarity).

6ub9, resolution 2.78Å

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