5o4u

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The flagellin of Pyrococcus furiosusThe flagellin of Pyrococcus furiosus

Structural highlights

5o4u is a 16 chain structure with sequence from Pyrococcus furiosus dsm 3638. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[A0A0B4ZYM1_PYRFU] Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.[RuleBase:RU361282]

Publication Abstract from PubMed

The archaellum is the macromolecular machinery that Archaea use for propulsion or surface adhesion, enabling them to proliferate and invade new territories. The molecular composition of the archaellum and of the motor that drives it appears to be entirely distinct from that of the functionally equivalent bacterial flagellum and flagellar motor. Yet, the structure of the archaellum machinery is scarcely known. Using combined modes of electron cryo-microscopy (cryoEM), we have solved the structure of the Pyrococcus furiosus archaellum filament at 4.2 A resolution and visualise the architecture and organisation of its motor complex in situ. This allows us to build a structural model combining the archaellum and its motor complex, paving the way to a molecular understanding of archaeal swimming motion.

Structure and in situ organisation of the Pyrococcus furiosus archaellum machinery.,Daum B, Vonck J, Bellack A, Chaudhury P, Reichelt R, Albers SV, Rachel R, Kuhlbrandt W Elife. 2017 Jun 27;6. pii: e27470. doi: 10.7554/eLife.27470. PMID:28653905[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

See Also

References

  1. Daum B, Vonck J, Bellack A, Chaudhury P, Reichelt R, Albers SV, Rachel R, Kuhlbrandt W. Structure and in situ organisation of the Pyrococcus furiosus archaellum machinery. Elife. 2017 Jun 27;6. pii: e27470. doi: 10.7554/eLife.27470. PMID:28653905 doi:http://dx.doi.org/10.7554/eLife.27470

5o4u, resolution 4.20Å

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