6que

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Structure of ovine transhydrogenase in the presence of NADP+ in a "single face-down" conformationStructure of ovine transhydrogenase in the presence of NADP+ in a "single face-down" conformation

Structural highlights

6que is a 2 chain structure with sequence from Ovis aries. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[NNTM_SHEEP] The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity). May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland (By similarity).[UniProtKB:P07001][UniProtKB:Q13423]

6que, resolution 3.70Å

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OCA