Crystal structure of dmNxf2 UBA domain fused with Panoramix helixCrystal structure of dmNxf2 UBA domain fused with Panoramix helix

Structural highlights

6opf is a 4 chain structure with sequence from Drome. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:Panx, CG9754 (DROME)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[NXF2_DROME] May be involved in the export of mRNA from the nucleus to the cytoplasm.[1]

References

  1. Herold A, Klymenko T, Izaurralde E. NXF1/p15 heterodimers are essential for mRNA nuclear export in Drosophila. RNA. 2001 Dec;7(12):1768-80. PMID:11780633

6opf, resolution 2.00Å

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OCA