1vol
TFIIB (HUMAN CORE DOMAIN)/TBP (A.THALIANA)/TATA ELEMENT TERNARY COMPLEX
OverviewOverview
The crystal structure of the transcription factor IIB (TFIIB)/TATA box-binding protein (TBP)/TATA-element ternary complex is described at 2.7 A resolution. Core TFIIB resembles cyclin A, and recognizes the preformed TBP-DNA complex through protein-protein and protein-DNA interactions. The amino-terminal domain of core TFIIB forms the downstream surface of the ternary complex, where it could fix the transcription start site. The remaining surfaces of TBP and the TFIIB can interact with TBP-associated factors, other class II initiation factors, and transcriptional activators and coactivators.
About this StructureAbout this Structure
1VOL is a Protein complex structure of sequences from Arabidopsis thaliana and Homo sapiens. The following page contains interesting information on the relation of 1VOL with [TATA-Binding Protein]. Full crystallographic information is available from OCA.
ReferenceReference
Crystal structure of a TFIIB-TBP-TATA-element ternary complex., Nikolov DB, Chen H, Halay ED, Usheva AA, Hisatake K, Lee DK, Roeder RG, Burley SK, Nature. 1995 Sep 14;377(6545):119-28. PMID:7675079 Page seeded by OCA on Thu Apr 24 09:40:21 2008