Crystal structure of S. cerevisiae DEAH-box RNA helicase Dhr1, essential for small ribosomal subunit biogenesisCrystal structure of S. cerevisiae DEAH-box RNA helicase Dhr1, essential for small ribosomal subunit biogenesis

Structural highlights

6h57 is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Activity:RNA helicase, with EC number 3.6.4.13
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[DHR1_YEAST] Probable ATP-binding RNA helicase. Required for 18S rRNA synthesis. May play a role in restructuring of the pre-rRNA.[1]

References

  1. Colley A, Beggs JD, Tollervey D, Lafontaine DL. Dhr1p, a putative DEAH-box RNA helicase, is associated with the box C+D snoRNP U3. Mol Cell Biol. 2000 Oct;20(19):7238-46. doi: 10.1128/mcb.20.19.7238-7246.2000. PMID:10982841 doi:http://dx.doi.org/10.1128/mcb.20.19.7238-7246.2000

6h57, resolution 2.30Å

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OCA