4rsn

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Crystal structure of the E267V mutant of cytochrome P450 BM3Crystal structure of the E267V mutant of cytochrome P450 BM3

Structural highlights

4rsn is a 2 chain structure with sequence from Atcc 14581. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:cyp102, cyp102A1, p450bm-3 (ATCC 14581)
Activity:Unspecific monooxygenase, with EC number 1.14.14.1
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[CPXB_BACME] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450.

See Also

4rsn, resolution 2.70Å

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