M. thermoresistible GuaB2 delta-CBS in complex with inhibitor Compound 14 (VCC900455)M. thermoresistible GuaB2 delta-CBS in complex with inhibitor Compound 14 (VCC900455)

Structural highlights

6d4q is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[G7CNL4_MYCT3] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]

6d4q, resolution 1.71Å

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OCA