6me4
XFEL crystal structure of human melatonin receptor MT1 in complex with 2-iodomelatoninXFEL crystal structure of human melatonin receptor MT1 in complex with 2-iodomelatonin
Structural highlights
Function[MTR1A_HUMAN] High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. |
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Large Structures
- Batyuk, A
- Brehm, W
- Cherezov, V
- Gati, C
- Grandner, J M
- Grant, T D
- Han, G W
- Ishchenko, A
- Johansson, L C
- Katritch, V
- Liu, W
- Madsen, C
- McCorvy, J D
- Michaelian, N
- Olsen, R H.J
- Patel, N
- Roth, B L
- Stauch, B
- Tribo, A R
- Weierstall, U
- White, T A
- Zhu, L
- 2-iodomelatonin
- Circadian rhythm
- Gpcr
- Jetlag
- Lcp
- Membrane protein
- Pg
- Xfel