4le8

Structure of the Als3 adhesin from Candida albicans, residues 1-299 (mature sequence)Structure of the Als3 adhesin from Candida albicans, residues 1-299 (mature sequence)

Structural highlights 4le8 is a 2 chain structure with sequence from candida_stellatoidea Atcc 11006 candida stellatoidea. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Related: 4leb, 4lee Gene: ALD8, ALS3 (ATCC 11006 Candida stellatoidea) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [ALS3_CANAX] Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells (By similarity).

spinqualitylabelsall models 4le8, resolution 1.75Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image