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6f7f

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Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acidTryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid

Structural highlights

6f7f is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[TRPR_ECOLI] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

6f7f, resolution 2.13Å

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OCA
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