6dev

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Human caspase-6 E35KHuman caspase-6 E35K

Structural highlights

6dev is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Activity:Caspase-6, with EC number 3.4.22.59
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

6dev, resolution 2.35Å

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OCA