Crystal structure of the N-terminal domain of UPF0209 protein yfcK from Escherichia coli O157:H7Crystal structure of the N-terminal domain of UPF0209 protein yfcK from Escherichia coli O157:H7
Structural highlights
2qy6 is a 2 chain structure with sequence from Eco57. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
[MNMC_ECO57] Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.[HAMAP-Rule:MF_01102]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
