Hydroxymethylbilane synthaseHydroxymethylbilane synthase

Structural highlights

2ypn is a 1 chain structure with sequence from "bacillus_coli"_migula_1895 "bacillus coli" migula 1895. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:Hydroxymethylbilane synthase, with EC number 2.5.1.61
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[HEM3_ECOLI] Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.[HAMAP-Rule:MF_00260]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2ypn, resolution 2.30Å

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OCA